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Gene Information
Gene symbol: IL23A
Gene name: interleukin 23, alpha subunit p19
HGNC ID: 15488
Synonyms: SGRF, IL23P19, IL-23, IL-23A, P19
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IFNG | 1 hits |
| 2 | IL17A | 1 hits |
| 3 | IL4 | 1 hits |
| 4 | IL6 | 1 hits |
| 5 | SOCS6 | 1 hits |
| 6 | TH1L | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16358360 | IL-23, a proximal regulator of IL-17, may be a major driving force in the induction of autoimmune inflammation. |
| 2 | 16358360 | We provide the first evidence in an animal model that IL-23 is involved in the development of type-1 diabetes, by inducing IL-17 and possibly IFN-gamma production in the target tissue. |
| 3 | 19756989 | Oral OKT3 enhanced T cell proliferation, suppressed Th1 and Th17 responses by 43% and 41%, respectively, increased TGF-beta/IL-10 expression and decreased IL-23/IL-6 expression by dendritic cells, and affected the IgG repertoire as measured by antigen arrays. |
| 4 | 20498357 | Furthermore, the addition of TGF-beta to the Th17-inducing cytokines (IL-1beta, IL-6, IL-21, IL-23) that induce memory cells to secrete IL-17, resulted in the marked coexpression of IL-9 in IL-17 producing memory cells. |
| 5 | 20406305 | The inhibition of EAE by PPARdelta agonists was also associated with a decrease in IL-12 and IL-23 and an increase in IL-4 and IL-10 expression in the CNS and lymphoid organs. |
| 6 | 22069275 | STAT4 is involved in the signalling of interleukin-12 and ?IFN, as well as interleukin-23. |