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Gene Information
Gene symbol: INSIG2
Gene name: insulin induced gene 2
HGNC ID: 20452
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
15528275
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Herein, we identified a novel 1alpha,25-dihydroxyvitamin D3 [1,25-(OH)2D3] response element in the promoter region of Insig-2 gene, which specifically binds to the heterodimer of retinoid X receptor and vitamin D receptor (VDR) and directs VDR-mediated transcriptional activation in a 1,25-(OH)2D3-dependent manner.
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2 |
21812109
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By 6 ?h, acrolein altered hepatic gene expression including Insig1, Insig2 and Hmgcr genes and stimulated an acute-phase response (APR) with up-regulation of serum amyloid A genes (Saa) and systemic hypoalbuminemia.
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