Ignet

Gene symbol: IRAK1BP1

Gene name: interleukin-1 receptor-associated kinase 1 binding protein 1

HGNC ID: 17368

Synonyms: AIP70, SIMPL

Related Genes

Related Sentences

#	PMID	Sentence
1	17079333	SIMPL (signaling molecule that associates with mouse Pelle-like kinase) is a component of a signaling pathway through which tumor necrosis factor-alpha (TNF-alpha) induces NF-kappaB-controlled gene transcription.
2	17079333	SIMPL interacts with the nuclear pool of the NF-kappaB subunit, p65, in a TNF-alpha-dependent manner to enhance p65-dependent gene transcription.
3	17079333	SIMPL mutants lacking sites of TNF-alpha-enhanced phosphorylation impaired nuclear localization and prevented TNF-alpha-induced p65 transactivation activity.