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Gene Information

Gene symbol: IRF3

Gene name: interferon regulatory factor 3

HGNC ID: 6118

Related Genes

# Gene Symbol Number of hits
1 IFNG 1 hits
2 IL1B 1 hits
3 NFKB1 1 hits
4 TLR3 1 hits
5 TLR4 1 hits

Related Sentences

# PMID Sentence
1 18223009 TLR3 signaling mediated PICex-induced nuclear factor-kappaB (NF-kappaB) and IRF-3 activation and beta-cell apoptosis.
2 18223009 PICin activated NF-kappaB and IRF-3 in a TLR3-independent manner, induced eukaryotic initiation factor 2 alpha phosphorylation, and triggered a massive production of interferon (IFN)-beta.
3 21700474 Interestingly, the results indicated that beneficial effects of rosiglitazone on LPS-induced inflammation in VSMCs were mediated via interference of TLR4 and its downstream signaling components including Toll-interleukin-1 (IL-1) receptor domain-containing adaptor inducing interferon-? (TRIF), interferon regulatory factor 3 (IRF3) and interferon-gamma inducible protein 10 (IP-10).