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Gene Information
Gene symbol: IRF4
Gene name: interferon regulatory factor 4
HGNC ID: 6119
Synonyms: LSIRF
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21111405
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Interferon Regulatory Factor (IRF4) is a crucial regulator of IL-17 and IL-21 production.
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2 |
21111405
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We recently found that the serine-threonine kinase ROCK2 phosphorylates IRF4 and regulates its ability to control IL-17 and IL-21 production.
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3 |
21111405
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We furthermore demonstrate that ROCK inhibition corrects the abnormal IRF4 function in NOD T cells and diminishes their production of IL-17 and IL-21.
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4 |
21647406
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Importantly, levels of IRF4 and IRF8 expression were lower in tolerogenic bone marrow derived DCs (BMDCs) generated with GM-CSF as compared to immunogenic BMDCs generated with GM-CSF and IL-4.
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