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Gene Information

Gene symbol: IRF4

Gene name: interferon regulatory factor 4

HGNC ID: 6119

Synonyms: LSIRF

Related Genes

# Gene Symbol Number of hits
1 CSF2 1 hits
2 IL17A 1 hits
3 IL17C 1 hits
4 ROCK2 1 hits

Related Sentences

# PMID Sentence
1 21111405 Interferon Regulatory Factor (IRF4) is a crucial regulator of IL-17 and IL-21 production.
2 21111405 We recently found that the serine-threonine kinase ROCK2 phosphorylates IRF4 and regulates its ability to control IL-17 and IL-21 production.
3 21111405 We furthermore demonstrate that ROCK inhibition corrects the abnormal IRF4 function in NOD T cells and diminishes their production of IL-17 and IL-21.
4 21647406 Importantly, levels of IRF4 and IRF8 expression were lower in tolerogenic bone marrow derived DCs (BMDCs) generated with GM-CSF as compared to immunogenic BMDCs generated with GM-CSF and IL-4.