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Gene Information
Gene symbol: IRGM
Gene name: immunity-related GTPase family, M
HGNC ID: 29597
Synonyms: LRG47, LRG-47, IFI1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21530739
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The immune system continuously monitors resident microbiota and utilizes constitutive antimicrobial mechanisms to maintain immune homeostasis. associations between IBD and genes that regulate microbial recognition and innate immune pathways, such as nucleotide oligomerization domain 2 (Nod2), genes that control autophagy (eg, ATG16L1, IRGM), and genes in the interleukin-23-T helper cell 17 pathway indicate the important roles of host-microbe interactions in regulating intestinal immune homeostasis.
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