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Gene Information
Gene symbol: ITGB2
Gene name: integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
HGNC ID: 6155
Synonyms: LFA-1, MAC-1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
16129698
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Six weeks after STZ injection, impairment of left ventricular (LV) function parameters measured by a Millar-tip catheter (peak LV systolic pressure; dP/dtmax; dP/dtmin) was accompanied by a significant increment of ICAM-1 and VCAM-1 (CAMs) expression, as well as of beta2-leukocyte-integrins+ (CD18+, CD11a+, CD11b+) and cytokine (TNF-alpha and IL-1beta)-expressing infiltrates in male Sprague-Dawley (SD-STZ) rats compared with normoglycemic littermates.
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2 |
19553613
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Inhibition of ICAM-1/CD18 signaling suppresses but does not completely abolish the cardinal manifestations of diabetic retinopathy, suggesting a role for additional adhesion molecules.
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