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Gene Information
Gene symbol: KCNJ3
Gene name: potassium inwardly-rectifying channel, subfamily J, member 3
HGNC ID: 6264
Synonyms: Kir3.1, GIRK1, KGA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | SREBF1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19423844 | Western blot analysis of extracts of Akita mice demonstrated that insulin treatment increased the expression of GIRK1, SREBP-1, and I(KAch) activity in atrial myocytes from these mice to levels in wild-type mice. |
| 2 | 19423844 | Insulin treatment of cultured atrial myocytes stimulated GIRK1 expression 2.68+/-0.12-fold (P<0.01), which was reversed by overexpression of dominant negative SREBP-1. |
| 3 | 19423844 | These results support a unique molecular mechanism for insulin regulation of GIRK1 expression and parasympathetic response via SREBP-1, which might play a role in the pathogenesis of DAN in response to insulin deficiency in the diabetic heart. |