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Gene Information
Gene symbol: KIF5B
Gene name: kinesin family member 5B
HGNC ID: 6324
Synonyms: KNS
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
20870970
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Suppression of Kinesin-1 by antisense oligonucleotides, or overexpression of dominant-negative acting kinesin heavy chain, has been reported to affect the sustained phase of glucose-stimulated insulin secretion in ?-cells in vitro.
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2 |
20870970
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However, compared with controls, pancreas of Kif5b(fl/)?:RIP2-Cre mice exhibited both reduced islet size and increased islet number, concomitant with an increased insulin vesicle density in ?-cells.
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3 |
20870970
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In addition to being essential for maintaining glucose homeostasis and regulating ?-cell function, Kif5b may be involved in ?-cell development by regulating ?-cell proliferation and insulin vesicle synthesis.
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