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Gene Information

Gene symbol: KLF2

Gene name: Kruppel-like factor 2 (lung)

HGNC ID: 6347

Synonyms: LKLF

Related Genes

# Gene Symbol Number of hits
1 ADIPOQ 1 hits
2 MAP2K5 1 hits
3 MAPK7 1 hits
4 PPARA 1 hits

Related Sentences

# PMID Sentence
1 12426306 In this study, we identify that a second family member, KLF2/Lung Krüppel-like factor (LKLF), as a negative regulator of adipocyte differentiation.
2 20693579 Taken together, these findings suggest that the inhibition of adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by UVA occurs primarily through the reduced expression of PPAR ?, which is mediated by up-regulation of KLF2 via the activation of MIF-AMP-activated protein kinase signaling.
3 20671964 Furthermore, siRNA mediated ERK5 gene knockdown suppressed MEF2C and KLF2 expression and increased VEGF expression and angiogenesis.
4 20671964 On the other hand, constitutively active MEK5, an activator of ERK5, increased ERK5 activation and ERK5 and KLF2 mRNA expression and attenuated basal- and glucose-induced VEGF mRNA expression.