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Gene Information
Gene symbol: KLRK1
Gene name: killer cell lectin-like receptor subfamily K, member 1
HGNC ID: 18788
Synonyms: NKG2D, KLR, NKG2-D, CD314
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD8A | 1 hits |
| 2 | KIR3DL1 | 1 hits |
| 3 | KLRC2 | 1 hits |
| 4 | TNFRSF1A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18483268 | On the tumor cells, increased expression of an NKG2D ligand (Rae1gamma) and of a death receptor (TNFRSF1A) contributed to enhanced immune cell-mediated recognition and lysis. |
| 2 | 20061825 | NKG2D is a surface receptor expressed on NK cells but also on CD8(+) T cells, gammadelta T cells, and auto-reactive CD4(+)/CD28(-) T cells of patients with rheumatoid arthritis. |
| 3 | 20408863 | Interestingly, NKG2D expression was increased significantly (P<0.0001), whereas killer cell immunoglobulin-like receptor (KIR)3DL1 expression was decreased (P<0.0001) within the NK cell population. |
| 4 | 21741920 | Within hours of treatment initiation, NK cells of patients that had an early virological response increased expression of activating receptors NKG2D, NKp30, and CD16 and decreased expression of NKG2C and 2B4, along with inhibitory receptors SIGLEC7 and NKG2A, resulting in NK cell activation. |