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Gene Information

Gene symbol: LIPC

Gene name: lipase, hepatic

HGNC ID: 6619

Synonyms: HL, HTGL

Related Genes

# Gene Symbol Number of hits
1 CES1 1 hits
2 INS 1 hits
3 LPL 1 hits

Related Sentences

# PMID Sentence
1 759824 H-TGL was the lipase activity remaining after inhibition of lipoprotein lipase (LPL) by 1.0 M NaCl.
2 759824 The contributions of H-TGL and LPL to the total plasma triacylglycerol hydrolase (TGH) activity depend on the amount of heparin injected and the time of blood withdrawal after heparin injection.
3 3883096 Although LPL has been extensively studied in diabetes, the effect of insulinization on H-TGL activity has not been well characterized.
4 3883096 To determine whether H-TGL activity is altered in insulin-deficient diabetes, postheparin plasma was obtained from eight beagle dogs: three normal (nondiabetic) control dogs and five pancreatectomized diabetic dogs were studied acutely in poor diabetic control (underinsulinized), and again in short-term good control (well insulinized).
5 3883096 Thus, insulin-deficient diabetes in dogs increases H-TGL, and short-term improvement of glycemic control with insulin partially corrects this increase.
6 3584394 Body weight and insulin requirement correlated directly with HTGL activity and inversely with serum HDL cholesterol levels.
7 18436977 HTGL activity was high while LPL and LCAT activities were low in these rats.