- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: LTA
Gene name: lymphotoxin alpha (TNF superfamily, member 1)
HGNC ID: 6709
Synonyms: TNFSF1, LT
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DARC | 1 hits |
| 2 | ICAM1 | 1 hits |
| 3 | IDDM2 | 1 hits |
| 4 | IL1B | 1 hits |
| 5 | INS | 1 hits |
| 6 | PTPRC | 1 hits |
| 7 | TNF | 1 hits |
| 8 | TNFRSF1A | 1 hits |
| 9 | VCAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1996407 | Furthermore, the Mo IL-1 beta and TNF-alpha secretions of IDDM patients were significantly higher than the Mo secretions of TNF-beta genotype-matched healthy controls. |
| 2 | 1279667 | The expression of TNF-beta in the pancreas of transgenic mice resulted in a leukocytic inflammatory infiltrate consisting primarily of B220+ IgM+ B cells and CD4+ and CD8+ T cells. |
| 3 | 7682590 | The expression of the TNF-alpha transgene was restricted to the pancreas, in contrast to TNF-beta expression from the same promoter, in which the transgene was expressed in the pancreas, kidney, and skin. |
| 4 | 7682590 | Both TNF-alpha and TNF-beta transgenic mice show elevated expression of leukocyte adhesion molecules VCAM-1 and ICAM-1 in islet endothelia and increased expression of MHC class I on islet cells. |
| 5 | 9174153 | Insulin-dependent diabetes mellitus (IDDM) and Graves' disease (GD) are autoimmune endocrinopathies and associated with distinct HLA-DR and -DQ alleles as well as several tumor necrosis factor alpha (TNF-alpha) and beta (TNF-beta) alleles. |
| 6 | 9174153 | TNF-alpha and TNF-beta interact with TNF receptor (TNF-R), of which two subtypes have been described: TNF-R1 and TNF-R2. |
| 7 | 16468038 | It has been suggested that the gene encoding lymphotoxin-alpha (LTA) is associated with insulin resistance, and genetic association studies in the LTA region offer some support for this. |
| 8 | 16468038 | However, LTA is in linkage disequilibrium with both the HLA gene cluster and the gene encoding TNF-alpha, making inferences about causality difficult. |
| 9 | 19680232 | Herpes virus entry mediator (HVEM) is a member of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF14), which serves as a receptor for herpes viruses and cytokines such as lymphotoxin-alpha (LT-alpha) and LIGHT (lymphotoxin-like inducible protein that competes with glycoprotein D for herpes virus entry on T cells). |