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Gene Information
Gene symbol: LY96
Gene name: lymphocyte antigen 96
HGNC ID: 17156
Synonyms: MD-2
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
20959532
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Moreover, data from transient transfection experiments suggest that TLR6 is required for TLR2 and MD2 for TLR4 to augment inflammation in FFA- and glucose-exposed cells.
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2 |
19201903
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In this study, we demonstrated that lactate stimulated MD-2, a coreceptor for TLR4 signaling activation, NF-kappaB transcriptional activity, and the expression of inflammatory genes in human U937 histiocytes (resident macrophages).
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3 |
19201903
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Collectively, this study documents that lactate boosts TLR4 activation and NF-kappaB-dependent inflammatory gene expression via monocarboxylate transporters and MD-2 up-regulation.
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