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Gene Information

Gene symbol: LY96

Gene name: lymphocyte antigen 96

HGNC ID: 17156

Synonyms: MD-2

Related Genes

# Gene Symbol Number of hits
1 NFKB1 1 hits
2 TLR4 1 hits
3 TLR6 1 hits

Related Sentences

# PMID Sentence
1 20959532 Moreover, data from transient transfection experiments suggest that TLR6 is required for TLR2 and MD2 for TLR4 to augment inflammation in FFA- and glucose-exposed cells.
2 19201903 In this study, we demonstrated that lactate stimulated MD-2, a coreceptor for TLR4 signaling activation, NF-kappaB transcriptional activity, and the expression of inflammatory genes in human U937 histiocytes (resident macrophages).
3 19201903 Collectively, this study documents that lactate boosts TLR4 activation and NF-kappaB-dependent inflammatory gene expression via monocarboxylate transporters and MD-2 up-regulation.