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Gene Information
Gene symbol: MAP3K3
Gene name: mitogen-activated protein kinase kinase kinase 3
HGNC ID: 6855
Synonyms: MAPKKK3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | MAPK1 | 1 hits |
| 3 | NFKB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18593820 | Overexpression of MEKK3, a possible mediator from the TNF-alpha receptor to the JNK/p38 and NK-kappaB signaling cascade, increased the levels of phospho-JNK, phospho-p38, and NF-kappaB, and reduced the glucose-stimulated Ca(2)(+) influx and GSIS. |
| 2 | 20720201 | MEKK3 knockdown leads to reversal of the deviated IKK and MAPKs activation, resulting in reduced IL-12 production and decreased CD4(+) Tconv cell proliferation. |