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Gene Information

Gene symbol: MC1R

Gene name: melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)

HGNC ID: 6929

Synonyms: MSH-R

Related Genes

# Gene Symbol Number of hits
1 ASIP 1 hits
2 MC4R 1 hits
3 POMC 1 hits

Related Sentences

# PMID Sentence
1 1314697 Taken together, these results suggest that NDP-MSH, alpha-MSH, and DAB389-MSH bind to a common melanotropin receptor in human metastatic melanoma cells.
2 21460229 These mutations have been described as suppressors of ASP action, blocking its antagonizing effects on the melanocortin 1 and 4 receptors (MC1R and MC4R) in the skin and the brain, respectively, via unknown mechanisms.
3 11837451 The yellow coat colour is the result of agouti chronically antagonizing the binding of alpha-MSH to Mc1r and the obese phenotype results from agouti protein antagonizing the binding of alpha-MSH to Mc3r and/or Mc4r.