Gene Information
Gene symbol: MDM2
Gene name: Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
HGNC ID: 6973
Synonyms: HDM2, HDMX, MGC5370
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
15140202
|
Cerebral proteasome function is reduced and ubiquitin and p53 accumulate in these brain regions, with the subsequent activation of a p53-dependent transgene and the endogenous Mdm2 gene.
|
2 |
21123956
|
Statins has been demonstrated to facilitate p53 degradation by activating its specific ubiquitin ligase, MDM2.
|
3 |
21123956
|
The p53 expression level in the ischemic limb of ATR-treated KK/Ay was significantly decreased and MDM2 phosphorylation level was markedly increased in tandem with the activation of Akt.
|