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Gene Information

Gene symbol: MDM2

Gene name: Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)

HGNC ID: 6973

Synonyms: HDM2, HDMX, MGC5370

Related Genes

# Gene Symbol Number of hits
1 AKT1 1 hits
2 RPS27A 1 hits
3 TP53 1 hits

Related Sentences

# PMID Sentence
1 15140202 Cerebral proteasome function is reduced and ubiquitin and p53 accumulate in these brain regions, with the subsequent activation of a p53-dependent transgene and the endogenous Mdm2 gene.
2 21123956 Statins has been demonstrated to facilitate p53 degradation by activating its specific ubiquitin ligase, MDM2.
3 21123956 The p53 expression level in the ischemic limb of ATR-treated KK/Ay was significantly decreased and MDM2 phosphorylation level was markedly increased in tandem with the activation of Akt.