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Gene Information

Gene symbol: MFN2

Gene name: mitofusin 2

HGNC ID: 16877

Synonyms: CPRP1, KIAA0214, MARF, CMT2A2

Related Genes

# Gene Symbol Number of hits
1 PGC 1 hits
2 PPARGC1A 1 hits
3 PPARGC1B 1 hits

Related Sentences

# PMID Sentence
1 19448711 Estrogen-related receptor-alpha transcription factor is a key regulator of Mfn2 transcription and recruits peroxisome proliferator-activated receptor gamma coactivator (PGC)-1beta and PGC-1alpha.
2 19448711 We propose that PGC-1beta is a regulator of normal expression of Mfn2 in muscle, whereas PGC-1alpha participates in the stimulation of Mfn2 expression under a variety of conditions characterized by enhanced energy expenditure.
3 20032281 CONCLUSIONS Our results demonstrate alterations in the regulatory pathway that controls PGC-1alpha expression and induction of Mfn2 in muscle from patients with early-onset type 2 diabetes.