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Gene Information
Gene symbol: MIRN21
Gene name: microRNA 21
HGNC ID: 31586
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1S1 | 1 hits |
| 2 | HNF4A | 1 hits |
| 3 | IL1B | 1 hits |
| 4 | MIRN192 | 1 hits |
| 5 | PDCD4 | 1 hits |
| 6 | PTEN | 1 hits |
| 7 | REL | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22140441 | More detailed analysis showed that miR-34a and miR-21 both overexpressed in RCC cooperate in downregulation of the HNF4A mRNA. |
| 2 | 19424061 | Some promote matrix deposition (miR-192 and miR-377) or epithelial-to-mesenchymal transition (miR-200 and miR-205), whereas preliminary findings suggest others might serve protective roles (miR-21). miRNAs recently identified in urinary exosomes could potentially serve as disease biomarkers. |
| 3 | 20086228 | We found that IL-1beta and TNF-alpha induce the expression of miR-21, miR-34a, and miR-146a both in MIN6 cells and human pancreatic islets. |
| 4 | 21613227 | Renal cortices from OVE26 type 1 diabetic mice showed significantly elevated levels of miR-21 associated with reduced PTEN and increased fibronectin content. |
| 5 | 21613227 | Interestingly, high glucose-stimulated miR-21 inactivated PRAS40, a negative regulator of TORC1. |
| 6 | 21730150 | In pancreatic ? cells, c-Rel and p65 of the NF-?B family activated the mir21 gene promoter and increased miR-21 RNA levels; miR-21 in turn decreased the level of PDCD4, which is able to induce cell death through the Bax family of apoptotic proteins. |