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Gene Information
Gene symbol: MMP12
Gene name: matrix metallopeptidase 12 (macrophage elastase)
HGNC ID: 7158
Synonyms: HME
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | ITGAX | 1 hits |
| 3 | TGM2 | 1 hits |
| 4 | TIMP2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10807873 | Furthermore, Western blot analysis demonstrated that insulin increased MMP-12 protein production. |
| 2 | 16293556 | In pediatric patients, increased numbers of MMP-12 positive macrophages in lamina propria associate with high titers of antibodies to TG2 and proness to CD. |
| 3 | 20185806 | CD11c(+) eATMPhis expressed a mixed M1/M2 profile, with some M1 transcripts upregulated (IL-12p40 and IL-1beta), others downregulated (iNOS, caspase-1, MCP-1, and CD86), and multiple M2 and matrix remodeling transcripts upregulated (arginase-1, IL-1Ra, MMP-12, ADAM8, VEGF, and Clec-7a). |
| 4 | 21829729 | These remodeling indices were associated with increased expression of matrix regulatory proteins matrix metalloproteinase (MMP)-9, MMP-12, tissue inhibitors of matrix metalloproteinase (TIMP)-1, TIMP-2, and plasminogen activator inhibitor-1 (PAI-1) in db/db arteries. |