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Gene Information
Gene symbol: MMP14
Gene name: matrix metallopeptidase 14 (membrane-inserted)
HGNC ID: 7160
Synonyms: MT1-MMP
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
12958045
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In addition to upregulation of PAI-1, downregulation of MMP-2 and MT1-MMP might play a crucial role in coronary matrix remodeling in insulin-resistant diabetes.
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2 |
20379053
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AGE-induced RAGE expression, as well as other molecules, including membrane type 1-MMP (MT1-MMP), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1), was NADPH oxidase signaling-dependent and blunted by temocaprilat and olmesartan.
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3 |
21436261
|
Taken together, MMP14-dependent collagenolysis plays the major role in regulating adipogenic histone marks by releasing the epigenetic constraints imposed by fibrillar type I collagen.
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