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Gene Information
Gene symbol: MMP3
Gene name: matrix metallopeptidase 3 (stromelysin 1, progelatinase)
HGNC ID: 7173
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | COL1A1 | 1 hits |
| 3 | COL2A1 | 1 hits |
| 4 | GFAP | 1 hits |
| 5 | MAPK8 | 1 hits |
| 6 | MMP7 | 1 hits |
| 7 | MMP9 | 1 hits |
| 8 | TIMP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7533311 | Insulin treatment partially ameliorated the decrease in mRNA levels for MMP-1 and MMP-3 and the increase in those for TIMP-1 in the glomeruli of diabetic rats. |
| 2 | 11916931 | In obese mice, the expression of MMP-3, -11, -12, -13, and -14 and TIMP-1 mRNAs was upregulated, whereas that of MMP-7, -9, -16, and -24 and TIMP-4 was downregulated. |
| 3 | 15945009 | In the present study, the authors investigated the expression of various extracellular matrix components and in particular tenascin, fibronectin, laminin, collagen IV, and MMP-3 glycoprotein as well as the expression of glial fibrillary acidic protein in each type of epithelial membrane in order to elucidate the role of these molecules in the formation of these two types of membranes. |
| 4 | 17664271 | TNFalpha also led to activation of JNK with increased expression of the proinflammatory gene, monocyte chemoattractant protein-1 and matrix metalloproteinase 3, and beta-arrestin-1 knockdown inhibited both of these effects. |
| 5 | 17893005 | Composite MMP-9 genotypes but not other SNPs were associated with MI, whereas MMP-1/MMP-3 genotypes were CAD-associated. |
| 6 | 21227015 | In the asymptomatic diabetic patients, MMP3 correlated only with albuminuria (r = 0.341) and MMP9 only with HbA(1c) (r = 0.262); neither MMP was correlated with echocardiographic parameters of diastolic function. |
| 7 | 20664951 | Intra-articular injection with apelin in vivo up-regulated the expression of MMP-3, -9, and IL-1beta as well as decreased the level of collagen II. |
| 8 | 21853531 | Here, we identify the transcription factor retinoid-related orphan receptor gamma (ROR?) as a negative regulator of adipocyte differentiation through expression of its newly identified target gene matrix metalloproteinase 3. |