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Gene Information
Gene symbol: MMP7
Gene name: matrix metallopeptidase 7 (matrilysin, uterine)
HGNC ID: 7174
Synonyms: PUMP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD44 | 1 hits |
| 2 | INS | 1 hits |
| 3 | MMP3 | 1 hits |
| 4 | MYLK | 1 hits |
| 5 | NGF | 1 hits |
| 6 | SRF | 1 hits |
| 7 | STAT3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11916931 | In obese mice, the expression of MMP-3, -11, -12, -13, and -14 and TIMP-1 mRNAs was upregulated, whereas that of MMP-7, -9, -16, and -24 and TIMP-4 was downregulated. |
| 2 | 20110336 | We found that insulin resistance and agonist stimulation increased the expression and activity of MMPs (MMP-2 and MMP-7), the EGFR, contractile proteins such as myosin light chain kinase and MLC II, and their transcriptional activators including P90 ribosomal kinase (P90RSK) and serum response factor, possibly via the activation of extracellular signal-regulated kinase (ERK1/2) in VSMCs. |
| 3 | 20713153 | Chronic daily administration of high-molecular mass HA for 2 weeks significantly reduced CD44, PKC(?I), PKC(?II), and PKC? gene expression and the related protein production in kidney tissue and TNF-?, IL-6, IL-18, MMP-7, and iNOS expression and levels also decreased. |
| 4 | 20957344 | Diabetes-induced peroxynitrite formation impaired production and activity of matrix metalloproteinase-7 (MMP-7), which cleaves proNGF extracellularly, leading to accumulation of proNGF and reducing NGF in samples from diabetic retinopathy patients and experimental models. |
| 5 | 21481787 | Using a Kras-driven mouse model of PDA, we establish that the inflammatory mediator Stat3 is a critical component of spontaneous and pancreatitis-accelerated PDA precursor formation and supports cell proliferation, metaplasia-associated inflammation, and MMP7 expression during neoplastic development. |