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Gene Information
Gene symbol: MMRN1
Gene name: multimerin 1
HGNC ID: 7178
Synonyms: ECM, EMILIN4, GPIa*
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21526116
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Importantly, PVT1 knockdown significantly reduced mRNA and protein levels of the major ECM proteins, FN1 and COL4A1, and two key regulators of ECM proteins, TGFB1 and PAI-1.
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2 |
21526116
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However, we observed a higher and more rapid reduction in levels of secreted FN1, COL4A1, and PAI-1 compared with TGFB1, suggesting that at least some of the PVT1 effects on ECM proteins may be independent of this cytokine.
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3 |
21526116
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These results indicate that PVT1 may mediate the development and progression of diabetic nephropathy through mechanisms involving ECM accumulation.
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4 |
22045654
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Curcumin also attenuated the expression of TGF-?1, CTGF, osteopontin, p300 and ECM proteins such as fibronectin and type IV collagen.
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