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Gene Information
Gene symbol: MT-CO2
Gene name: mitochondrially encoded cytochrome c oxidase II
HGNC ID: 7421
Synonyms: COX2, CO2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AVP | 1 hits |
| 2 | GSK3B | 1 hits |
| 3 | PTGS2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15585669 | COX2 inhibition completely prevented polyuria and PGE(2) excretion in COX1-/- mice, suggesting that COX2, but not COX1, plays a critical role in lithium-induced polyuria. |
| 2 | 15585669 | Lithium also induced renal medullary COX2 protein expression in congenitally polyuric antidiuretic hormone (AHD)-deficient rats, demonstrating that lithium-induced COX2 protein expression is not secondary to altered ADH levels or polyuria. |
| 3 | 15585669 | Lithium also decreased renal medullary GSK-3beta activity, and this was temporally related to increased COX2 expression in the kidney from lithium-treated mice, consistent with a tonic in vivo suppression of COX2 expression by GSK-3 activity. |