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Gene Information
Gene symbol: NDN
Gene name: necdin, melanoma antigen (MAGE) family member
HGNC ID: 7675
Synonyms: HsT16328, PWCR
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | DLK1 | 1 hits |
| 3 | E2F4 | 1 hits |
| 4 | INS | 1 hits |
| 5 | IRS1 | 1 hits |
| 6 | WNT10A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16505226 | E2F4 expression was decreased by 10-fold in muscle and 2.5-fold in adipose tissue; necdin was identified in adipose tissue only and increased 1.8-fold after TZD treatment. |
| 2 | 16505226 | These data suggest that changes in necdin and E2F4 expression after rosiglitazone exposure in humans are associated with altered adipocyte differentiation and may contribute to improved insulin sensitivity in humans treated with TZDs. |
| 3 | 15895078 | Necdin is also markedly increased in Irs knockout cells that cannot differentiate, and knockdown of necdin restores brown adipogenesis with downregulation of Pref-1 and Wnt10a expression. |
| 4 | 21862615 | A constitutively active form of CREB expressed in IRS-1 knockout cells decreased necdin promoter activity, necdin mRNA, and necdin protein levels, leading to a partial restoration of differentiation. |