Ignet

Gene Information

Gene symbol: NGF

Gene name: nerve growth factor (beta polypeptide)

HGNC ID: 7808

Related Genes

#	Gene Symbol	Number of hits
1	BAX	1 hits
2	BCL2	1 hits
3	BDNF	1 hits
4	CALCA	1 hits
5	CASP3	1 hits
6	CAV1	1 hits
7	CCK	1 hits
8	EGR1	1 hits
9	FOS	1 hits
10	INS	1 hits
11	MMP7	1 hits
12	NGFR	1 hits
13	PCP4	1 hits
14	PRKCA	1 hits
15	TGFB2	1 hits
16	TNF	1 hits
17	TP53	1 hits

Related Sentences

#	PMID	Sentence
1	2478719	However, sphingosine, an inhibitor of protein kinase C and NGF-induced differentiation of PC 12 cells, did not alter the phosphorylation of proteins on tyrosine stimulated by NGF.
2	8243829	Exposure of all three beta-cell lines to nerve growth factor increased NGFI-A and c-fos mRNA steady-state levels, showing that these receptors are functional.
3	7513041	Treatment of diabetic rats with NGF also prevented the deficits in the levels of CGRP and gamma-PPT mRNA in the lumbar dorsal root ganglia (P < 0.05).
4	8158209	While the total or relative deficiency of insulin causes diabetes, the possible disorders due to deficiency of nerve growth factor have not been clearly defined.
5	10600222	We conclude that an increase in NGF and a suppression in TGF-beta2 levels are present in patients with type-1 diabetes mellitus and that both cytokines may play independent roles in the pathogenesis of this disease.
6	11422429	It has been suggested that insulin has an effect on nerve regeneration similar to that of nerve growth factor (NGF).
7	12769602	It has been demonstrated that CCK-8 counteracts neuronal deficit following chemical or surgical lesions in both the central and peripheral nervous systems and that Nerve Growth factor (NGF) is involved in the CCK-induced recovery process.
8	12679365	Intriguingly, nerve growth factor antagonized the enhanced mitogenic response of SCs to neuregulin1-beta1 and inhibited the glucose-induced down-regulation of Cav-1 transcription, mRNA, and protein expression through p75NTR-dependent activation of JNK.
9	16287464	To assess changes associated with diabetes in urinary bladder nerve-growth factor (NGF) and NGF receptor p75NTR expression using a streptozotocin (STZ)-induced diabetic rat model.
10	18180317	In addition, GLP-1 attenuated TNF-alpha-mediated induction of Nur77 mRNA and TNF-alpha-mediated binding of nuclear proteins (NPs) to the PAI-1, Nur77, cis-acting response element nerve growth factor induced clone B response element (NBRE).
11	19534294	It has been suggested that insulin has an effect on nerve regeneration similar to that of nerve growth factor (NGF).
12	20002474	Thus, we investigated the associations of serum NGF level and NGF receptor activity with the presence and severity of DPN.
13	21055431	With treatment of exendin-4 to the diabetic mice the following results were noted (i) NGF, TrkA and proliferating cell nuclear antigen positive hepatocytes were decreased; (ii) p75 neurotrophin receptor and caspase-3 positive hepatocyte could not be detected; (iii) liver alanine transaminase and aspartate transaminase activities, lipid peroxidation, protein carbonyl and myeloperoxidase levels were decreased; (iv) liver catalase, superoxide dismutase, glutathione peroxidase activities and glutathione levels were increased.
14	20007950	On the other hand, proteins seen or predicted to be up-regulated include proteins involved in cell apoptosis (e.g. p53, 14-3-3-gamma, Serpinf1, Cct4, Cct5, and Sepina3n), proteins that neutralize the biological activity of nerve growth factor (e.g. anti-NGF 30), and proteins involved in lipid metabolism (e.g. apoA-I and apoA-IV).
15	21500593	To explore the possible mechanism of nerve growth factor (NGF) mixed insulin on the angiogenesis of burn wounds and the effect on the expressions of Bcl-2 and Bax in diabetic rats.
16	21500593	A combination of NGF and insulin local application can enhance the angiogenesis of the burn wound in diabetic rats and accelerate wound healing by increasing the expression of Bcl-2 and decreasing the expression of Bax and restraining apoptosis of the wounds vascular endothelial cells of diabetic rats.
17	20957344	Diabetes-induced peroxynitrite formation impaired production and activity of matrix metalloproteinase-7 (MMP-7), which cleaves proNGF extracellularly, leading to accumulation of proNGF and reducing NGF in samples from diabetic retinopathy patients and experimental models.
18	20560879	TFL, MNCV, morphology of sciatic nerve, myelinated nerve fiber density and the expressions of nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) in soleus and sciatic nerve were measured at 10 weeks after diabetes induction.
19	21671256	When PCP4 expression was induced with doxcycline, neurite outgrowth was significantly advanced in the presence of nerve growth factor (NGF) and dibutyryl cAMP, which was inhibited by W-7, a calmodulin inhibitor, and PD98059, an ERK inhibitor.