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Gene Information
Gene symbol: NKX2-2
Gene name: NK2 homeobox 2
HGNC ID: 7835
Synonyms: NKX2.2
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
16873704
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We examined the association of variants in genes encoding several transcription factors (TCF1, TCF2, HNF4A, ISL1, IPF1, NEUROG3, PAX6, NKX2-2, NKX6-1, and NEUROD1) and genes encoding the ATP-sensitive K(+) channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) with type 2 diabetes in a Japanese cohort of 2,834 subjects.
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2 |
17456846
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Using this transgenic approach, we have determined that the Nkx2.2-repressor derivative disrupts endogenous Nkx2.2 expression in adult mice and causes downregulation of the mature beta-cell factors, MafA and Glut2.
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