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Gene Information

Gene symbol: NMB

Gene name: neuromedin B

HGNC ID: 7842

Synonyms: MGC2277, MGC3936, MGC17211

Related Genes

# Gene Symbol Number of hits
1 GRP 1 hits
2 GRPR 1 hits
3 NMBR 1 hits
4 VIP 1 hits

Related Sentences

# PMID Sentence
1 2539739 To identify receptors for bombesin-related peptides in the rat esophagus, we measured binding of 125I-Bolton-Hunter neuromedin B (125I-BH-neuromedin B) and 125I-[Tyr4]bombesin to tissue sections from the rat esophagus and compared the results with those for rat pancreas.
2 8380344 At 37 degrees C binding of 125I-[D-Tyr0]NMB to NMB-R or 125I-[Tyr4]Bn to GRP-R was maximal by 5-15 min and decreased to 60-70% after 60 min.
3 7794919 In binding studies the affinity of the mGRP-r in Sf9 cells for the agonists bombesin (Bn), GRP, and neuromedin B (NMB) varied differently with infection time: with Bn the affinity decreased 3-fold with longer infection times, with GRP it remained unchanged, and with NMB it decreased 10-fold.
4 7651888 BN, GRP, or neuromedin B (NMB), at concentrations up to 1 microM, did not stimulate pepsinogen release or affect the stimulation caused by vasoactive intestinal peptide (VIP) (100 nM) or CCK-8 (10 nM), respectively.
5 7562561 Recently it has been established that both a gastrin-releasing peptide (GRP) receptor and a neuromedin B (NMB) receptor mediate the actions of bombesin-related peptides in mammals.
6 7562561 No COOH-terminal fragments of NMB or GRP functioned as a GRP or NMB receptor antagonist.