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Gene Information
Gene symbol: NMBR
Gene name: neuromedin B receptor
HGNC ID: 7843
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GRP | 1 hits |
| 2 | GRPR | 1 hits |
| 3 | NMB | 1 hits |
| 4 | PLCB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8380344 | Both subtypes occur widely in GI tract and the CNS; however, in contrast to the GRP-R subtype little is known about the ligand-receptor interactions for the NMB-R. |
| 2 | 8380344 | At 37 degrees C binding of 125I-[D-Tyr0]NMB to NMB-R or 125I-[Tyr4]Bn to GRP-R was maximal by 5-15 min and decreased to 60-70% after 60 min. |
| 3 | 8163469 | While it is known that this receptor is coupled to phospholipase C, like many other phospholipase C-activating receptors, little is known about regulation of the NMB-R subsequent to agonist stimulation. |
| 4 | 7562561 | Recently it has been established that both a gastrin-releasing peptide (GRP) receptor and a neuromedin B (NMB) receptor mediate the actions of bombesin-related peptides in mammals. |
| 5 | 7562561 | No COOH-terminal fragments of NMB or GRP functioned as a GRP or NMB receptor antagonist. |
| 6 | 7562561 | These results demonstrate that none of the known strategies used to prepare peptide GRP receptor antagonists are successful at the NMB receptor, suggesting that a different strategy will be needed for this peptide, such as the formation of somatostatin octapeptide or D-amino acid-substituted substance P analogs. |