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Gene Information

Gene symbol: NOD2

Gene name: nucleotide-binding oligomerization domain containing 2

HGNC ID: 5331

Synonyms: BLAU, CD, PSORAS1, CLR16.3, NLRC2

Related Genes

# Gene Symbol Number of hits
1 ATG16L1 1 hits
2 INS 1 hits
3 IRGM 1 hits

Related Sentences

# PMID Sentence
1 21530739 The immune system continuously monitors resident microbiota and utilizes constitutive antimicrobial mechanisms to maintain immune homeostasis. associations between IBD and genes that regulate microbial recognition and innate immune pathways, such as nucleotide oligomerization domain 2 (Nod2), genes that control autophagy (eg, ATG16L1, IRGM), and genes in the interleukin-23-T helper cell 17 pathway indicate the important roles of host-microbe interactions in regulating intestinal immune homeostasis.
2 21715553 Insulin resistance was measured by hyperinsulinemic euglycemic clamps in mice injected with mimetics of meso-diaminopimelic acid-containing PGN or the minimal bioactive PGN motif, which activate NOD1 and NOD2, respectively.