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Gene Information
Gene symbol: NPC1L1
Gene name: NPC1-like 1
HGNC ID: 7898
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ABCG5 | 1 hits |
| 2 | ABCG8 | 1 hits |
| 3 | APOB | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16518588 | We examined expression of the following: (1) Niemann-Pick C1-like 1 (NPC1L1), which regulates cholesterol absorption; (2) ATP-binding cassette transporters G5 and G8 (ABCG5, ABCG8), which regulate cholesterol homeostasis through their ability to excrete enterocyte cholesterol back into the lumen of the intestine; and (3) microsomal triglyceride transfer protein (MTTP), which packages the chylomicron particle by assembling cholesterol, triglyceride, phospholipids and apolipoprotein B48. |
| 2 | 17109865 | In diabetic animals, HMGCoA reductase, MTTP and NPC1L1 mRNA were significantly elevated (p<0.02) and ABCG5 and ABCG8 were significantly reduced (p<0.02) in the liver. |