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Gene Information
Gene symbol: NPC2
Gene name: Niemann-Pick disease, type C2
HGNC ID: 14537
Synonyms: HE1, NP-C2, EDDM1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20650896 | The presence of NPC2 in mature white adipocytes was also necessary for their maintenance because silencing NPC2 in differentiated cells by siRNA stimulated PPARG expression, which was followed by a shift toward a more favorable, brown adipocyte-like metabolic state characterized by up-regulated lipolysis and increased insulin sensitivity. |
| 2 | 20650896 | Altogether, the current study highlights NPC2 as a novel intracrine/autocrine factor that controls adipocyte differentiation and function as well as potential therapeutic target for the treatment of type 2 diabetes and related metabolic disorders. |