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Gene Information
Gene symbol: NPPC
Gene name: natriuretic peptide C
HGNC ID: 7941
Synonyms: CNP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | INSR | 1 hits |
| 3 | NPPA | 1 hits |
| 4 | NPR2 | 1 hits |
| 5 | NPR3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8674895 | Insulin at a concentration in the physiological range (10(-10)-10(-7) mol/l) potently suppressed CNP secretion, whereas insulin at the same concentration did not suppress endothelin (ET) secretion from EC. |
| 2 | 8674895 | Insulin, therefore, can be a potent inhibitor of CNP secretion through the activation of insulin receptor. |
| 3 | 16436087 | The ANP and NPR-C mRNA expressions were only altered after 3 weeks, whereas BNP, CNP and NPR-A mRNA expressions were not altered in STZ-treated-mouse hearts at any of the time points. |
| 4 | 16904201 | Our results indicate that the cAMP production by NPR-C is not altered in DOCA-induced hypertension, since ANP(1-28), CNP(1-22) and C-ANP, which specifically bind to NPR-C, show a similar inhibitory effect on cAMP production stimulated by the physiological agonist histamine in glomeruli from DOCA-treated rats and controls. |
| 5 | 19418585 | The expression of CNP in gastric tissue was not changed in diabetic rats, however the expression of NPR-B was significantly increased in diabetic rats, and the staining indexes of NPR-B were 30.67 +/- 1.59 and 17.63 +/- 1.49 in diabetic and normal rat, respectively (n = 8, P < 0.01). |
| 6 | 21938932 | In the myocardium of diabetic rats, the weakening of GC stimulating effect of ANP and, on the contrary, the strengthening of CNP effect were observed. |
| 7 | 21938932 | In the ovaries, GC stimulating effect of CNP and, to a lesser degree, the corresponding effect of ANP were decreased. |