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Gene Information
Gene symbol: NPR3
Gene name: natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
HGNC ID: 7945
Synonyms: GUCY2B, FLJ14054
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CAPN1 | 1 hits |
| 2 | EGF | 1 hits |
| 3 | FOS | 1 hits |
| 4 | NPPA | 1 hits |
| 5 | NPPB | 1 hits |
| 6 | NPPC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16436087 | The ob/ob-mice with type-II diabetes displayed highly significant increases of the cardiac mRNA expression of NPR-B and NPR-C while the expression levels of NPR-A, ANP, BNP, and CNP mRNA were similar in ob/ob-mice and controls. |
| 2 | 16904201 | Our results indicate that the cAMP production by NPR-C is not altered in DOCA-induced hypertension, since ANP(1-28), CNP(1-22) and C-ANP, which specifically bind to NPR-C, show a similar inhibitory effect on cAMP production stimulated by the physiological agonist histamine in glomeruli from DOCA-treated rats and controls. |
| 3 | 11457715 | These studies suggest that EGF potentiates the ANP glomerular effects in diabetes by inhibition of its degradation by mesangial NPR-C via a mechanism involving AP-1. |