Gene Information
Gene symbol: NR2C2
Gene name: nuclear receptor subfamily 2, group C, member 2
HGNC ID: 7972
Synonyms: TAK1, TR2R1, hTAK1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21478464
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We investigated the roles of hepatic TR4 in the regulation of lipogenesis and insulin sensitivity in vivo and in vitro.
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2 |
21478464
|
TR4 transactivation is inhibited via phosphorylation by metformin-induced AMP-activated protein kinase (AMPK) at the amino acid serine 351, which results in the suppression of SCD1 gene expression.
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3 |
21478464
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Additional mechanistic dissection finds TR4-transactivated SCD1 promoter activity via direct binding to the TR4-responsive element located at -243 to -255 on the promoter region.
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