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Gene Information
Gene symbol: NSF
Gene name: N-ethylmaleimide-sensitive factor
HGNC ID: 8016
Synonyms: SKD2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | SLC2A4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15935991 | Transfections of rat adipose cells demonstrate that over-expression of wild-type NSF has no effect on total, or basal and insulin-stimulated cell-surface expression of HA-tagged GLUT4. |
| 2 | 15935991 | In contrast, a dominant-negative NSF (NSF-D1EQ) can be expressed at a low enough level that it has little effect on total HA-GLUT4, but does reduce both basal and insulin-stimulated cell-surface HA-GLUT4 by approximately 50% without affecting the GLUT4 fold-translocation response to insulin. |
| 3 | 15935991 | Thus, our data demonstrate that the multiple fusion steps in GLUT4 trafficking have differential quantitative requirements for NSF activity. |