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Gene Information
Gene symbol: ODC1
Gene name: ornithine decarboxylase 1
HGNC ID: 8109
Synonyms: ODC
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKR1B1 | 1 hits |
| 2 | ALB | 1 hits |
| 3 | CASP3 | 1 hits |
| 4 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 6445842 | Insulin treatment within 10 h of the SZ injection prevented the increase of ODC activity; however, insulin given after enzyme activity had increased did not restore ODC activity to control levels. |
| 2 | 7018971 | Addition of insulin and amino acids had no effect; however, 50% rat serum increased ODC activity four- to seven-fold after the initial decrease. |
| 3 | 7018971 | These findings suggest that insulin modulates the synthesis of ODC via production of a second circulating factor, the activity of which is diminished in serum of diabetic rats. |
| 4 | 7026548 | When glucagon or insulin was given to pancreatectomized rats, dietary induction of ODC was restored to a level found in normal rats. |
| 5 | 7026548 | These results suggest that increased influx of amino acids into liver is a critical factor for dietary induction of ODC and that both glucagon and insulin play a role in stimulating amino acid influx. |
| 6 | 2146735 | We measured ODC activity, of ventricular homogenates obtained from diabetic SHR and nonhypertensive WKY rats, with and without chronic treatment with insulin or triiodothyronine (T3). |
| 7 | 2146735 | Both T3 and insulin therapy prevented the decline in ventricular ODC activity in both strains, although only the effect of insulin was correlated with LVW. |
| 8 | 2128196 | The present study was designed to investigate if the aldose reductase inhibitor ponalrestat is capable of preventing the impairment of the response of ornithine decarboxylase (ODC) to nerve crush in streptozotocin (STZ)-diabetic rats. 2. |
| 9 | 1511780 | However, in muscle from diabetic animals the ODC activity declined steadily during the 14 days to 34% of control values (P less than 0.01), and insulin treatment completely normalized the ODC activity in muscle. |
| 10 | 8447376 | Insulin treatment normalized renal ODC activity, whereas DFMO treatment totally inhibited the kidney ODC activity. |
| 11 | 8447376 | Insulin treatment normalized both kidney weight and kidney ODC activity. |
| 12 | 7796931 | Finally, the urinary albumin excretion was markedly increased in diabetic rats with no effects of ODC-inhibition. |
| 13 | 7796931 | In conclusion, inhibition of ODC initiated in diabetic rats with manifest kidney enlargement had no effect on renal size, glomerular volume or urinary albumin excretion. |
| 14 | 11230775 | Ornithine decarboxylase (ODC) activity, ratio of fragmented DNA to total DNA, electrophoresis of fragmented DNA, and Western blot analysis of caspase-3 were examined. |