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Gene Information
Gene symbol: OGG1
Gene name: 8-oxoguanine DNA glycosylase
HGNC ID: 8125
Synonyms: HMMH, HOGG1, OGH1, MUTM
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18599524
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In the renal cortex of diabetic rats, the increase in Akt phosphorylation is associated with enhanced phosphorylation of tuberin, decreased OGG1 protein expression, and 8-oxodG accumulation.
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2 |
18599524
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High glucose also resulted in downregulation of OGG1 protein expression, paralleling its effect on Akt and tuberin.
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3 |
18599524
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Inhibition of phosphatidylinositol 3-kinase/Akt significantly reduced high glucose-induced tuberin phosphorylation and restored OGG1 expression.
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4 |
18599524
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Hydrogen peroxide stimulates Akt and tuberin phosphorylation and decreases OGG1 protein expression.
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