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Gene Information

Gene symbol: OGG1

Gene name: 8-oxoguanine DNA glycosylase

HGNC ID: 8125

Synonyms: HMMH, HOGG1, OGH1, MUTM

Related Genes

# Gene Symbol Number of hits
1 AKT1 1 hits
2 TSC2 1 hits

Related Sentences

# PMID Sentence
1 18599524 In the renal cortex of diabetic rats, the increase in Akt phosphorylation is associated with enhanced phosphorylation of tuberin, decreased OGG1 protein expression, and 8-oxodG accumulation.
2 18599524 High glucose also resulted in downregulation of OGG1 protein expression, paralleling its effect on Akt and tuberin.
3 18599524 Inhibition of phosphatidylinositol 3-kinase/Akt significantly reduced high glucose-induced tuberin phosphorylation and restored OGG1 expression.
4 18599524 Hydrogen peroxide stimulates Akt and tuberin phosphorylation and decreases OGG1 protein expression.