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Gene Information

Gene symbol: OPRK1

Gene name: opioid receptor, kappa 1

HGNC ID: 8154

Synonyms: KOR

Related Genes

#	Gene Symbol	Number of hits
1	GAST	1 hits
2	INS	1 hits
3	PPY	1 hits

Related Sentences

#	PMID	Sentence
1	7009280	The intragastric administration of naloxone (4 mg), a specific opiate receptor antagonist, reduced the insulin response and augmented the glucagon response to the digested gluten test meal, whereas the response of both hormones to the undigested gluten meal was not affected by naloxone.
2	6295856	In search of possible factors which impair insulin release, we have investigated the effect of naloxone, a specific opiate receptor blocker, on insulin responses to glucose in subjects with non-insulin-dependent diabetes, as well as in normal subjects.
3	6143305	The present study was designed to determine the effect of naloxone, a specific opiate receptor antagonist, on postprandial levels of insulin, glucagon, pancreatic polypeptide (PP), somatostatin-like immunoreactivity (SLI) and gastrin in response to carbohydrate and fat-rich test meals in a group of 6 healthy volunteers.
4	3032718	The opiate receptor antagonist naloxone (1 mg/kg intraperitoneally) rapidly and transiently raised glucose and suppressed insulin concentrations in lean mice, and produced qualitatively similar but more protracted response in ob/ob mice.