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Gene Information
Gene symbol: OSM
Gene name: oncostatin M
HGNC ID: 8506
Synonyms: MGC20461
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CISH | 1 hits |
| 2 | INS | 1 hits |
| 3 | SOCS3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20651008 | Increased suppressor of cytokine signaling (SOCS) 3 expression negated IL-6 and OSM effects and significantly reduced cellular apoB mRNA abundance. |
| 2 | 21519329 | OSM in turn attenuated insulin-dependent Akt activation and, as a downstream target, glucokinase induction in hepatocytes, most likely by inducing suppressor of cytokine signaling 3 (SOCS3). |
| 3 | 21519329 | Thus, induction of OSM production in Kupffer cells by an autocrine PGE(2)-dependent feed-forward loop may be an additional, thus far unrecognized, mechanism contributing to hepatic insulin resistance and the development of NASH. |