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Gene Information

Gene symbol: P2RY2

Gene name: purinergic receptor P2Y, G-protein coupled, 2

HGNC ID: 8541

Synonyms: P2U

Related Genes

#	Gene Symbol	Number of hits
1	NOS3	1 hits
2	PTGS1	1 hits
3	PTGS2	1 hits
4	SLC29A1	1 hits

Related Sentences

#	PMID	Sentence
1	11909821	Our findings demonstrate that inhibition of adenosine transport via hENT1 in endothelial cells cultured in 25 mmol/L D-glucose could be due to stimulation of P2Y2 purinoceptors by ATP, which is released from these cells in response to D-glucose.
2	19188511	These experiments identified P2Y1, P2Y2, and possibly P2Y4 as the purinergic receptors involved in eNOS phosphorylation and demonstrated that this process was adenosine independent.
3	21856926	In arteries from GK rats (vs. those from Wistar rats), 1) ATP- and UTP-induced contractions, which were blocked by the nonselective P2 antagonist suramin, were enhanced, and these enhancements were suppressed by endothelial denudation, by cyclooxygenase (COX) inhibitors, or by a cytosolic phospholipase A(2) (cPLA(2)) inhibitor; 2) both nucleotides induced increased release of PGE(2) and PGF(2?); 3) nucleotide-stimulated cPLA(2) phosphorylations were increased; 4) COX-1 and COX-2 expressions were increased; and 5) neither P2Y2 nor P2Y6 receptor expression differed, but P2Y4 receptor expression was decreased.