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Gene Information
Gene symbol: P2RY6
Gene name: pyrimidinergic receptor P2Y, G-protein coupled, 6
HGNC ID: 8543
Synonyms: P2Y6
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | CASP3 | 1 hits |
| 3 | PRKCA | 1 hits |
| 4 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12825835 | We recently reported that the activation by UDP of rat P2Y6 nucleotide receptors expressed in 1321N1 astrocytoma cells protected them from TNFalpha-induced apoptosis by suppressing activation of caspase 3 and 8. |
| 2 | 12825835 | Cell death was induced in 1321N1 astrocytoma cells permanently expressing the rat P2Y6 receptor by exposure to TNFalpha in the presence of cycloheximide. |
| 3 | 12825835 | The activation of P2Y6 receptors by UDP both protected the astrocytes from TNF-alpha induced apoptosis and activated protein kinase C (PKC) isotypes. |
| 4 | 12825835 | The antiapoptotic protein, Akt, was not affected by P2Y6 receptor activation. |