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Gene Information
Gene symbol: PCNA
Gene name: proliferating cell nuclear antigen
HGNC ID: 8729
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BAD | 1 hits |
| 2 | CAT | 1 hits |
| 3 | CD68 | 1 hits |
| 4 | CDKN1A | 1 hits |
| 5 | DTL | 1 hits |
| 6 | FGF1 | 1 hits |
| 7 | FOXO1 | 1 hits |
| 8 | INS | 1 hits |
| 9 | KRT10 | 1 hits |
| 10 | SERPINH1 | 1 hits |
| 11 | SPP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22140505 | Confocal microscopy, real-time PCR and western blotting analyses revealed increased expression of PCNA and down-regulation of p27-Kip1 and altered expression of insulin receptors, insulin receptor substrate-2 and phosphorylated BAD. |
| 2 | 12947320 | We characterized immunohistochemically the expression of cell cycle regulators p63, CD29, PCNA, p53, pro- and antiapoptotic proteins bcl2, bax, caspase 3 and DNA breaks, as well as keratin 10, 16 and 17. |
| 3 | 16896921 | The purpose of this study was to measure and immunolocalize RAGE in normal and cataractous canine LECs, and to determine whether there was a correlation between RAGE and DNA damage (gadd45), cell-cycle regulation (p21), and LEC proliferation (proliferating cell nuclear antigen, PCNA). |
| 4 | 18471361 | Immunohistochemistry and Western blotting were used to detect the protein expression of OPN, CD68, and proliferating cell nuclear antigen (PCNA). |
| 5 | 18471361 | The protein of PCNA were also higher than that of control group 1 and 2 weeks after STZ injection (all P<0.05), and the increase in CD68 was observed at week 4 and week 8. |
| 6 | 19109737 | Treatment with high glucose alone (HG) or GI but not HI (high insulin alone) decreased EPC proliferation and their expression of cyclin E, cdk2 and PCNA compared to control. |
| 7 | 19902175 | Fibroblast apoptosis was measured by the TUNEL assay, proliferation by detection of proliferating cell nuclear antigen, and forkhead box O1 (FOXO1) activity by DNA binding and nuclear translocation. |
| 8 | 21055431 | With treatment of exendin-4 to the diabetic mice the following results were noted (i) NGF, TrkA and proliferating cell nuclear antigen positive hepatocytes were decreased; (ii) p75 neurotrophin receptor and caspase-3 positive hepatocyte could not be detected; (iii) liver alanine transaminase and aspartate transaminase activities, lipid peroxidation, protein carbonyl and myeloperoxidase levels were decreased; (iv) liver catalase, superoxide dismutase, glutathione peroxidase activities and glutathione levels were increased. |
| 9 | 19458120 | In addition, MnTMPyP administration significantly attenuated the increases of alpha-smooth muscle actin, PCNA, S100A4, CD68, and heat shock protein 47 expression following I/R. |
| 10 | 21641072 | The preliminary mechanism that aFGF helps to promote healing of diabetic ulcer is possibly associated with that aFGF stimulated ulcer skins to secrete TGF-? and PCNA proteins and promoted proliferation of capillaries and fibroblasts. |
| 11 | 21803027 | In this regard, VCN-2 in combination with DTL synergistically inhibited the growth of prostate tumors in vivo with a greater decrease in the levels of AR, pIGF1R, pAkt, PCNA, cyclin D1, Ki67, CD31, and increase in E-cadherin. |