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Gene Information
Gene symbol: PECAM1
Gene name: platelet/endothelial cell adhesion molecule 1
HGNC ID: 8823
Synonyms: CD31
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTB | 1 hits |
| 2 | ANGPT2 | 1 hits |
| 3 | CD34 | 1 hits |
| 4 | COL1A1 | 1 hits |
| 5 | CTGF | 1 hits |
| 6 | HIF1A | 1 hits |
| 7 | HMOX1 | 1 hits |
| 8 | ICAM1 | 1 hits |
| 9 | IFNG | 1 hits |
| 10 | IL1B | 1 hits |
| 11 | NOS3 | 1 hits |
| 12 | PTGS2 | 1 hits |
| 13 | STN | 1 hits |
| 14 | TGFA | 1 hits |
| 15 | TNF | 1 hits |
| 16 | VCAM1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21255215 | The decrease in circulating EMPs CD31+ [intergroup difference, -32 counts/µl (95% CI -51 to -9)] and the increase in EPCs CD34+/KDR+ [intergroup difference, 33 cells/10(6) events (95% CI 13 to 55)] were greater with pioglitazone versus metformin. |
| 2 | 9844140 | At the transcriptional level short-time exposure of endothelial cells to advanced glycated fibronectin and inflammatory mediators resulted in an increased expression of E-selectin, ICAM-1 and VCAM-1 mRNA levels, whereas PECAM-1 repeatedly showed a significant decrease of gene transcript levels. |
| 3 | 14527361 | Expression of PECAM-1 mRNA was measured by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) with beta-actin as an internal standard, and sequencing of RT-PCR products was performed to confirm the specificity of amplification for PECAM-1 gene. |
| 4 | 14527361 | However, PECAM-1 expression was reduced in the cells treated with TNF-alpha, IFN-gamma, TNF-alpha + IFN-gamma and AGEs-BSA + TNF-alpha. |
| 5 | 16546241 | Platelet activity was assessed by ADP-, and collagen-induced conventional plasma aggregometry, and by whole blood flow cytometry measuring expression of PECAM-1, GPIb, GP IIb/IIIa antigen and activity, vitronectin, P-selectin, LAMP-1, GP 37, LAMP-3, activated and intact PAR-1 thrombin receptors, GPIV, and platelet-monocyte formation. |
| 6 | 16916501 | Niacin reduced TNF-alpha-induced rise in ICAM-1 levels by 66% to 89% (p<0.0001), but did not significantly affect TNF-alpha-induced rise in PECAM-1. |
| 7 | 17488882 | In conclusion, HO-1 and eNOS are relevant targets for D-4F and may contribute to the D-4F-mediated increase in TM and CD31(+), the antioxidant and anti-inflammatory properties, and confers robust vascular protection in this animal model of type 1 diabetes. |
| 8 | 18316203 | Additionally, the statin augmented breaking strength and PECAM-1 immunostaining at day 12. |
| 9 | 19729486 | Confocal microscopy and real-time PCR showed that transforming growth factor (TGF)-beta1 induced de novo expression of alpha-SMA and loss of expression of VE-cadherin and CD31 in MMECs and primary cultures of renal endothelial cells in a time- and dose-dependent fashion. |
| 10 | 20814070 | In rats with chronic ulcers, the mRNA expression of HIF-1alpha, IL-1beta and COX-2 was assessed by RT-PCR and protein expression of platelet endothelial cell adhesion molecule-1 (PECAM-1), COX-2 and cNOS was examined by Western blot. |
| 11 | 11310829 | The overexpression of Ang-2 in the presence of markedly reduced VEGF in wounds of diabetic mice was associated with a dramatic decrease in endothelial cell numbers compared with normal healing as assessed by analysis of the endothelium-specific markers CD31 and von Willebrand factor, whereas the lymphatic endothelium remained stable as determined by expression of VEGF receptor-3 (VEGFR-3/Flt-4). |
| 12 | 21628879 | Fondaparinux treatment significantly suppressed urinary protein, glomerular hypertrophy, fibrin deposition, expression of connective tissue growth factor, and ECM proteins deposition together with CD31-positive capillaries. |