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Gene Information
Gene symbol: PLD1
Gene name: phospholipase D1, phosphatidylcholine-specific
HGNC ID: 9067
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | FKBP8 | 1 hits |
| 2 | MTTP | 1 hits |
| 3 | PIK3CG | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20189175 | Indeed, defective activation of PI3-kinase, secondary to insulin resistance, is associated with a reduction of apoB degradation in the hepatocytes, a rise in MTP expression (by increasing nuclear transcription factors Fox01 and Foxa2) and an increased activity of phospholipase D1 and ARF-1, which are involved in VLDL(1) formation. |
| 2 | 18765678 | In addition, Rheb-GTP stimulates phospholipase D1 to generate phosphatidic acid, a positive effector of mTORC1 activation, and binds to the mTOR inhibitor FKBP38, to displace it from mTOR. |