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Gene Information

Gene symbol: PPP1R14A

Gene name: protein phosphatase 1, regulatory (inhibitor) subunit 14A

HGNC ID: 14871

Synonyms: CPI-17

Related Genes

# Gene Symbol Number of hits
1 EDN1 1 hits
2 MYL6B 1 hits
3 PRKCA 1 hits
4 RHOA 1 hits

Related Sentences

# PMID Sentence
1 16205724 ET-1 increased particulate PKCalpha and epsilon to a similar extent in arteries from control and diabetic rats.NA significantly enhanced CPI-17 phosphorylation from a basal level of 22+/-10 to 71+/-7% of total in arteries from diabetic rats, and this was prevented by PKC inhibition.
2 16336954 Moreover, inhibiting either RhoA with C3 exoenzyme or ROCK with Y-27632 or H-1152 for 30 min diminished high glucose-induced CPI-17 phosphorylation.
3 16336954 Inhibiting protein kinase C (PKC) with GF109203X for 30 min did not inhibit high glucose-induced CPI-17 phosphorylation.
4 16204412 Our results also suggest that this high basal MLC phosphorylation may be due to the upregulation of Rho-kinase and CPI-17.
5 21756365 Our model was used to predict enhanced MLC activation by CPI-17 over-expression and by synergistic action of thrombin and VEGF at low mediator levels.