Gene Information
Gene symbol: PRDM16
Gene name: PR domain containing 16
HGNC ID: 14000
Synonyms: MEL1, PFM13, KIAA1675, MGC166915
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18719589
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BMP7 activates a full program of brown adipogenesis including induction of early regulators of brown fat fate PRDM16 (PR-domain-containing 16; ref. 4) and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha; ref. 5), increased expression of the brown-fat-defining marker uncoupling protein 1 (UCP1) and adipogenic transcription factors PPARgamma and CCAAT/enhancer-binding proteins (C/EBPs), and induction of mitochondrial biogenesis via p38 mitogen-activated protein (MAP) kinase-(also known as Mapk14) and PGC-1-dependent pathways.
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