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Gene Information

Gene symbol: PRDM16

Gene name: PR domain containing 16

HGNC ID: 14000

Synonyms: MEL1, PFM13, KIAA1675, MGC166915

Related Genes

# Gene Symbol Number of hits
1 BMP7 1 hits

Related Sentences

# PMID Sentence
1 18719589 BMP7 activates a full program of brown adipogenesis including induction of early regulators of brown fat fate PRDM16 (PR-domain-containing 16; ref. 4) and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha; ref. 5), increased expression of the brown-fat-defining marker uncoupling protein 1 (UCP1) and adipogenic transcription factors PPARgamma and CCAAT/enhancer-binding proteins (C/EBPs), and induction of mitochondrial biogenesis via p38 mitogen-activated protein (MAP) kinase-(also known as Mapk14) and PGC-1-dependent pathways.