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Gene Information
Gene symbol: PRKCE
Gene name: protein kinase C, epsilon
HGNC ID: 9401
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DGAT1 | 1 hits |
| 2 | DGAT2 | 1 hits |
| 3 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17526931 | Because Dgat catalyzes triglyceride synthesis from diacylglycerol, and because we have hypothesized that diacylglycerol accumulation triggers fat-induced hepatic insulin resistance through protein kinase C epsilon activation, we next sought to understand the paradoxical reduction in diacylglycerol in Dgat2 ASO-treated rats. |
| 2 | 17526931 | Taken together, these data suggest that knocking down Dgat2 protects against fat-induced hepatic insulin resistance by paradoxically lowering hepatic diacylglycerol content and protein kinase C epsilon activation through decreased SREBP1c-mediated lipogenesis and increased hepatic fatty acid oxidation. |