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Gene Information
Gene symbol: PROX1
Gene name: prospero homeobox 1
HGNC ID: 9459
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADRA2A | 1 hits |
| 2 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20419449 | In addition, the PROX1 glucose-raising allele showed a 2.9% decreased corrected insulin response (p = 0.03), while the hyperglycaemic allele of variants in or near ADRA2A, FADS1, CRY2 and C2CD4B were associated with a 2.6% to 9.3% decrease in one or both of two different OGTT-based disposition indices (p < 0.02 for all). |
| 2 | 20185807 | Abnormalities in early insulin secretion were suggested in glucose-raising allele carriers at MTNR1B, GCK, FADS1, DGKB, and PROX1 (lower insulinogenic index; no association with proinsulin or insulin sensitivity). |
| 3 | 21887289 | The diabetogenic alleles of DGKB and PROX1 were nominally associated with reduced insulin secretion. |
| 4 | 21887289 | Nominally significant effects on insulin sensitivity could be found for MADD and PROX1. |